Endometriosis – Causes, Symptoms And Treatment

Endometriosis is the growth of cells similar to those that form the inside of the uterus (endometrial cells), but in a location outside of the uterus. Endometrial cells are the same cells that are shed each month during menstruation. Endometriosis is a common health problem in women. In women with this problem, tissue that looks and acts like the lining of the uterus grows outside of the uterus in other areas. These areas can be called growths, tumors, implants, lesions, or nodulesIt facilitates collaboration and information sharing between women with endometriosis. Endometriosis is estimated to affect over one million women (estimates range from 3% to 18% of women) in the United States.

It is one of the leading causes of pelvic pain and reasons for laparoscopic surgery and hysterectomy in this country. While the mean age at diagnosis is around 25-30 years, endometriosis has been reported in girls as young as 11 years of age. Endometriosis is rare in postmenopausal women. Endometrial cells (loosened during menstruation) may “back up” through the fallopian tubes into the pelvis, where they implant and grow in the pelvic or abdominal cavities. This is called retrograde-menstruation. When endometrial tissue is located elsewhere in your body, it continues to act in its normal way: It thickens, breaks down and bleeds each month as your hormone levels rise and fall. Because there’s nowhere for the blood from this displaced tissue to exit your body.

It becomes trapped.Trapped blood may lead to the growth of cysts. Cysts, in turn, may form scar tissue and adhesions abnormal tissue that binds organs together. This process can cause pain in the area of misplaced tissue, often the pelvis, especially during your period. Scars and adhesions related to endometriosis also can cause fertility problems. Pain is one of the most common symptoms of endometriosis. Usually the pain is in the abdomen, lower back, and pelvis. Some women have no pain, even though their disease affects large areas. Other women with endometriosis have severe pain even though they have only a few small growths. Women with endometriosis may also have gastrointestinal problems such as diarrhea, constipation, or bloating, especially during their periods.

Causes of Endometriosis

1.Estrogen harmones

2.Retrograde menstruation.

3.Immune system

4.Allergic reactions.

5.Impact of toxins.

Symptoms of Endometriosis

1.Pain with sex.



4.Painful urination during periods.


Treatment of Endometriosis

Progesterone counteracts estrogen and inhibits the growth of the endometrium. Such therapy can reduce or eliminate menstruation in a controlled and reversible fashion. Progestins are chemical variants of natural progesterone. Gonadotropin releasing hormone agonists (GnRH agonists) induce a profound hypoestrogenism by decreasing FSH and LH levels. While quite effective, they induce unpleasant menopausal symptoms, and over time may lead to osteoporosis. Laparotomy can be used for more extensive surgery either in attempt to restore normal anatomy, or at least preserve reproductive potential. Danazol (Danocrine) and gestrinone are suppressive steroids with some androgenic activity. Both agents inhibit the growth of endometriosis but their use remains limited as they may cause hirsutism. There has been some research done at Case Western Reserve University on a topical Danocrine, applied locally, which has not produced the hirsutism characteristics. Pseudopregnancy can be created using oral contraceptives containing estrogen and progesterone. Women take the medicine consistently for 6 to 9 months. This type of therapy relieves most of the symptoms, but does not prevent scarring from the disease.

Avoid coffee and alcohol. Conservative surgery removes endometrial growths, scar tissue and adhesions without removing your reproductive organs. In laparoscopic surgery, a slender viewing instrument (laparoscope) is inserted through a small incision near your navel. The laparoscope is equipped with a laser, a cautery an instrument that destroys tissue with heat or small surgical instruments. Melatonin and serotonin are increased by meditation, and the stress hormone cortisol is decreased. Oral contraceptive pills (estrogen and progesterone in combination) are also sometimes used to treat endometriosis. The most common combination used is in the form of the oral contraceptive pill (OCP). Treatment of endometriosis has involved the administration of drugs known as aromatase inhibitors (anastrozole [Arimidex] and letrozole [Femara] are examples). These drugs act by interrupting local estrogen formation within the endometriosis implants themselves. They also inhibit estrogen production in the ovary, brain, and other sources, such as adipose tissue.

Things To Know About Real Estate Loans

Investing in real estate is quite expensive. Most people cannot afford to buy real estate with cash. With a real estate loan, the dream of your own property can be realized.

Many agencies such as banks, credit unions and lending companies offer real estate loans to those who can avail it. There are certain qualifications in order to qualify for a real estate loan.

Real estate loan is a loan on real estate usually secured by a legal document by which the owner transfers to the lender an interest in the real estate to secure the repayment of a debt or mortgage. There are two classifications of real estate loans: commercial and residential real estate loans.

In order to qualify for any of those two classifications of real estate loans the following are some of the requirements needed:

Commercial real estate loan:

Commercial real estate loan application form and real estate addendum.

Current business financial statements and most recent year tax return.

Guarantor’s current personal financial statement and most recent year personal tax return.

The applicant should sign the application form and the application materials should be submitted to the agency or institution where the applicant wants to apply for a commercial real estate loan.

Residential real estate loan:

Residential real estate loan application form.
Financial statement and most recent year income tax return.
Guarantor’s current personal financial statement and most recent year personal tax return.

In the same way as commercial real estate loans, the application materials for residential real estate loans should be submitted to the agency or institution where the applicant wants to apply for a residential real estate loan.

The materials needed for a real estate loan varies according to the requirements of different agencies and institutions.
Whn applying for a real estate loan, there are certain steps that the applicant should follow.

The following are the simple steps that an applicant should follow in order to hasten the processing of the real estate loan.

Select terms. Mortgage terms affect both interest rate and payment. With large amount of flexibility, lenders allow the applicant to tailor the loan to fit the budget needs.

Research the lender. In order for the applicant to save money, the easiest way to purchase real property in low rates is by finding the lowest costing loan. Research and find lenders who offer low cost loans.

Apply for real estate loan. After finding the right lender, the applicant can now apply for real estate loan accompanied with the requirements.

There are common mistakes when applying for a real estate loan. The following are some of it. To make the right impression and secure the loan, it is important to be aware of these common mistakes.
Not thoroughly researching the options. Thorough research on options should be made.

Not having the ducks in a row. Make sure that all the documentation the lender would expect is at hand and an applicant should be prepared to show why the property makes fiscal sense.

Failing to negotiate the best deal. Negotiation should be done to have the best deal.

Not selecting the best lawyer. Hiring the best lawyer is important. Hire lawyer that is very experienced in negotiating the types of real estates loans.

Going straight to a family lender. It is good to have a rapport with a lender, particularly when loan is needed. However, there are new real estate products offered constantly, ant it is worth the time to check out some of the other possibilities before going straight to favorite lender.

Knowing everything about real estate loans is very important when investing in real estate. Make sure you follow all the steps mentioned above.

Getting Over Someone

Basic question here: how can I tell when I’m over someone and ready to be with someone else?

- C.G., Boston, MA

That is a basic question, but not a simple one. I’m not sure I can even answer it.

Sometimes hearing someone else’s experiences put things in perspective. Here is a situation concerning a person I dated, how I personally view it, and how I make it work for me. Maybe this example will help clear things up a little bit for you too.

In my life, I’ve seen a lot of relationships and been envious of very few. I see a lot of phoniness, relationships of convenience, and people together for all the wrong reasons.

But I knew that my relationship with her was something incredibly, incredibly special. I’d never felt anything like that; it was something totally different than all the rest I’d ever been in. It was comparing apples to oranges, as the saying goes.

In every way, I found her to be the most beautiful thing that I’d ever seen. We showed each other our best and our worst and remained together because we believed in each other as individuals and believed in us as a couple.

It’s interesting to think of all the things we are taught and all we are not. People are taught a million things growing up: how to read, how to use a stove without burning their hands, how to fold a towel, how to drive, and so on.

But we’re never taught some of the things that are imperative in relationships; we’re somehow expected to learn them as we go and by trial and error. I, like many others, never learned how to trust someone to give them all of my feelings, so I’d always held something back, which isn’t fair.

I also never learned how to forgive someone that I loved when they hurt me. And I certainly never learned what to do when you find someone who is perfect for you. It sounds like such a great thing, but it can be one of the most overwhelming feelings you ever experience because you want it to work out more than you want anything else in your life.

And sometimes, by the time you start to realize these things, it’s too late to make everything right.

Making her cry was the worst thing I’ve ever done and just thinking about it hurts me more than anything I’ve ever lost, never achieved, failed at, or I could really explain here.

And now she’s gone. We had talked about “forever” but this isn’t the kind of “forever” I thought we meant.

Who we were at the time we made our memories, we’ll always be – that man will always love that woman and that woman will always love him just as much. I still miss so many things about her, namely counting on – and believing in – us.

I still think about her every day and wonder, wonder, and wonder. I made her an enormous part of my life and now that she’s gone, that life as I knew it is too.

The pain is normal. But don’t think that because you feel pain you can’t move on. What happened between the two of you obviously affected you, so the hurting is expected. Truthfully, and unfortunately, it may be felt for a long, long time.

If you think about it, you probably still don’t feel great about the moment you found out you didn’t get that job you really wanted or a pet that died when you were a kid. You may never feel perfectly fine about this situation either.

What I realized, and what you must too, is that you have to move on. They have. They have their own life going, and whether it’s them being alone or them being with someone else – it’s still them being without you.

There is no other option; you can’t stay closed off and emotionally unavailable forever in hopes they will change their mind about you or that it will work out somehow. Knowing when to let go and move forward it is the hard part.

You don’t want to do it when you’re emotionally unavailable, angry at life, or will be anything but the best person you can be to whomever it is you end up with next. I don’t know if you’re there. Maybe you don’t even know if you’re there.